868 research outputs found

    Survival of bacterial isolates exposed to simulated Jovian trapped radiation belt electrons and solar wind protons

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    With missions to Jupiter, the spacecraft will be exposed for extended duration to solar wind radiation and the Jovian trapped radiation belt. This study is designed to determine the effect of these radiation environments on spacecraft bacterial isolates. The information can be used in the probability of contamination analysis for these missions. A bacterial subpopulation from Mariner Mars 1971 spacecraft (nine sporeforming and three nonsporeforming isolates) plus two comparative organisms, Staphylococcus epidermidis ATCC 17917 and a strain of Bacillus subtilis var. niger, were exposed to 2-, 12-, and 25-MeV electrons at different doses with simultaneous exposure to a vacuum of 0.0013 N/sqm at 20 and -20 C. The radioresistance of the subpopulation was dependent on the isolate, dose, and energy of electrons. Temperature affected the radioresistance of only the sporeforming isolates. Survival data indicated that spores were reduced approximately 1 log/1500 J/kg, while nonsporeforming isolates (micrococci) were reduced 1.5 to 2 logs/1500 J/kg with the exception of an apparent radioresistant isolate whose resistance approached that of the spores. The subpopulation was found to be less resistant to lower energy than to higher energy electrons

    Creating Open Digital Library Using XML: Implementation of OAi-PMH Protocol at CERN

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    This article describes the implementation of the OAi-PMH protocol within the CERN Document Server (CDS). In terms of the protocol, CERN acts both as a data provider and service provider and the two core applications are described. The application of XML Schema and XSLT technology is emphasized

    Congruency effect between articulation and grasping in native English speakers

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    Previous studies have shown congruency effects between specific speech articulations and manual grasping actions. For example, uttering the syllable [kɑ] facilitates power grip responses in terms of reaction time and response accuracy. A similar association of the syllable [ti] with precision grip has also been observed. As these congruency effects have been to date shown only for Finnish native speakers, this study explored whether the congruency effects generalize to native speakers of another language. The original experiments were therefore replicated with English participants (N=16). Several previous findings were reproduced, namely the association of syllables [kɑ] and [ke] with power grip and of [ti] and [te] with precision grip. However, the association of vowels [ɑ] and [i] with power and precision grip, respectively, previously found for Finnish participants, was not significant for English speakers. This difference could be related to ambiguities of English orthography and pronunciation variations. It is possible that for English speakers seeing a certain written vowel activates several different phonological representations associated with that letter. If the congruency effects are based on interactions between specific phonological representations and grasp actions, this ambiguity might lead to weakening of the effects in the manner demonstrated here

    Development and pilot evaluation of a personalized decision support intervention for low risk prostate cancer patients.

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    ObjectivesDevelopment and pilot evaluation of a personalized decision support intervention to help men with early-stage prostate cancer choose among active surveillance, surgery, and radiation.MethodsWe developed a decision aid featuring long-term survival and side effects data, based on focus group input and stakeholder endorsement. We trained premedical students to administer the intervention to newly diagnosed men with low-risk prostate cancer seen at the University of California, San Francisco. Before the intervention, and after the consultation with a urologist, we administered the Decision Quality Instrument for Prostate Cancer (DQI-PC). We hypothesized increases in two knowledge items from the DQI-PC: How many men diagnosed with early-stage prostate cancer will eventually die of prostate cancer? How much would waiting 3 months to make a treatment decision affect chances of survival? Correct answers were: "Most will die of something else" and "A little or not at all."ResultsThe development phase involved 6 patients, 1 family member, 2 physicians, and 5 other health care providers. In our pilot test, 57 men consented, and 44 received the decision support intervention and completed knowledge surveys at both timepoints. Regarding the two knowledge items of interest, before the intervention, 35/56 (63%) answered both correctly, compared to 36/44 (82%) after the medical consultation (P = .04 by chi-square test).ConclusionsThe intervention was associated with increased patient knowledge. Data from this pilot have guided the development of a larger scale randomized clinical trial to improve decision quality in men with prostate cancer being treated in community settings
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